Search on: 3-ISOPROPYLMALATE DEHYDROGENASE 
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Descriptor English:   3-Isopropylmalate Dehydrogenase 
Descriptor Spanish:   3-Isopropilmalato Deshidrogenasa 
Descriptor Portuguese:   3-Isopropilmalato Desidrogenase 
Tree Number:   D08.811.682.047.500
Definition English:   An NAD+ dependent enzyme that catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate to 3-carboxy-4-methyl-2-oxopentanoate. It is involved in the biosynthesis of VALINE; LEUCINE; and ISOLEUCINE. 
History Note English:   2006(1980); use DICARBOXYLIC ACIDS 1970-1979 
Allowable Qualifiers English:  
administration & dosage adverse effects
antagonists & inhibitors analysis
biosynthesis blood
cerebrospinal fluid chemistry
classification chemical synthesis
contraindications drug effects
deficiency diagnostic use
economics genetics
history immunology
isolation & purification metabolism
pharmacology physiology
pharmacokinetics poisoning
radiation effects supply & distribution
secretion standards
toxicity therapeutic use
ultrastructure urine
Record Number:   50598 
Unique Identifier:   D050539 

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